The drug combination fenfluramine/phentermine, usually called fen-phen, was an anti-obesity treatment that utilized two anorectics. Fenfluramine was marketed by American Home Products (later known as Wyeth) as Pondimin, but was shown to cause potentially fatal pulmonary hypertension and heart valve problems, Phentermine: Adrenergic, dopaminergic, serot. Phentermine and topiramate, sold under the trade name Qsymia, is a combination medication used for weight loss. Phentermine and topiramate is associated with modest weight loss when compared with placebo. This weight loss was associated with improvements in weight-related comorbidities such as improved blood Phentermine: Appetite suppressant/stimulant of.
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Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called . Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication. The possibility of an association between PPH and the use of Phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who . Based on the reported excretion of Phentermine in urine, exposure increases can be expected in patients with renal impairment [see Clinical Pharmacology ()].
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